The art of deimmunizing therapeutic proteins

As designers of therapeutic proteins and antibodies, how can we take advantage of an immunological “short-cut”, to make our molecules less immunogenic?

Bioinformatics, Modeling & Simulation, Structural Biology, Immunotherapy, Protein EngineeringGordon WebsterSeptember 23, 2015

All Big Data is equal, but some Big Data may be more equal than others

It’s often widely assumed that decisions made by algorithms are more “neutral” and “fair” than those made by people.

Bioinformatics, Computational Biology, Mathematical Biology, Statistical AnalysisAlex LancasterSeptember 4, 2015computational biology, systems biology, bioinformatics, modeling, simulation, stochastic modeling, dynamic modeling, deterministic modeling, calculus, differential equations, big data, data science, data analysis

Biomarker Design: Lessons from Bayes' Theorem

Actionable insights that can be gained by the application of Bayesian analysis to the design of biomarkers ...

Bioinformatics, Biomarkers, Computational Biology, Mathematical Biology, Statistical AnalysisGordon WebsterAugust 14, 2015

Python for next-generation sequencing

A story about how a challenging genome sequencing project demonstrated once again, what an awesome tool Python can be ...